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Aromatic organic compounds that consist of a benzene ring with three hydroxyl functional group substitutions. Includes compounds that are derived from benzenetriols.
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AT-533 is a small-molecule inhibitor of Hsp90 with reported antiviral activity against herpes simplex virus (HSV). It suppresses tumor growth and angiogenesis by blocking the HIF-1α/VEGF/VEGFR-2 signaling pathway and inhibits downstream signaling including Akt/mTOR/p70S6K, Erk1/2, and FAK, making it useful as a research reagent in cell biology and preclinical studies.
Potent Hsp90 and HSV inhibitory activity.
Blocks HIF-1α/VEGF/VEGFR-2 signaling to suppress tumor growth and angiogenesis.
Inhibits downstream Akt/mTOR/p70S6K, Erk1/2, and FAK pathways.
Reduces tube formation, migration, and invasion in endothelial cell assays.
High purity suitable for research applications.
Stable as powder under recommended cold storage.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More